Home Mental Health Does Zoloft Motive Weight Acquire? — Talkspace

Does Zoloft Motive Weight Acquire? — Talkspace

Does Zoloft Motive Weight Acquire? — Talkspace


Printed on: 03 Apr 2023

Zoloft, sometimes called sertraline, is an antidepressant drugs used to regard melancholy, anxiousness, and different psychological fitness stipulations. Whilst this selective serotonin reuptake inhibitor (SSRI) may also be an efficient remedy of melancholy and anxiousness signs for many of us, like every drug, there are doable psychological and bodily Zoloft uncomfortable side effects that may include antidepressant use. A commonplace facet impact is Zoloft weight acquire. 

Now not everybody reports sertraline weight acquire. A lot of the time, analysis displays that frame weight acquire is discreet or brief. That mentioned, it’s nonetheless essential to grasp the prospective facet impact and talk about it along with your physician prior to beginning remedy.

Does Zoloft Motive Weight Acquire?

Are you able to acquire weight on Zoloft? Some research have proven that round 11% of people that take antidepressants revel in a weight acquire of no less than 5% all the way through the primary 12 months. Alternatively, your uncomfortable side effects might happen at other instances relying on how lengthy it takes for Zoloft to paintings on your frame. Some analysis additionally suggests that different varieties of antidepressants may have a better chance than Zoloft. 

“Zoloft can probably purpose weight acquire, however it’s now not a essential facet impact for everybody. It’s easiest to get readability out of your psychiatrist about which antidepressant is the most efficient are compatible for you. You’ll be able to get on any other drugs when you are gaining weight.”

Talkspace therapist Bisma Anwar, LMHC

What different SSRIs purpose weight acquire?

Frame weight acquire generally is a facet impact of antidepressant use past simply Zoloft. Different selective serotonin reuptake inhibitors (SSRIs) that may purpose weight acquire come with: 

  • Prozac
  • Paxil
  • Celexa
  • Lexapro 

Weight acquire seems to be much more likely when taking upper doses or for other people taking the antidepressant drug for prolonged classes.  


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Why Does Zoloft Motive Weight Acquire?

The precise reason it’s possible you’ll acquire weight on Zoloft isn’t absolutely understood, however a number of theories exist. 

Higher serotonin ranges

One principle means that larger serotonin ranges within the mind brought about by way of SSRI medicine can impact metabolism and starvation alerts within the frame. This may result in adjustments in urge for food and consuming conduct in addition to cravings for dangerous meals, leading to weight acquire over the years. 

Power ranges

Any other chance for Zoloft weight acquire is that sure varieties of melancholy medicines intrude with power stability. For some other people, antidepressant remedy might make them develop into much less lively and burn fewer energy than they typically would. 

Hormones and metabolism

A little analysis means that long-term use of SSRI medicine might adjust appetite-regulating hormones like leptin and ghrelin. Extra analysis is wanted, even though, because it’s unclear if this effects in weight acquire.  

Sedative impact

In any case, any other issue that would give a contribution to doable weight acquire from taking Zoloft may well be its sedative impact. Zoloft could make you are feeling drowsy or sleepy all the way through the day. It’s believable that this may cut back your job degree and building up your likelihood of gaining weight because of a loss of bodily workout.

How Can I Keep away from Gaining Weight on Zoloft?

If you happen to’re focused on Zoloft weight acquire, there are steps you’ll be able to take to lend a hand decrease this chance.

Nutritious diet

Keeping up a nutritious diet is essential to averting sertraline weight acquire. Consuming balanced foods with a number of end result, greens, lean proteins, and full grains will let you keep complete longer and stay your power ranges up. 

As well as, you must keep away from processed meals prime in sugar and saturated fat, as those can result in weight acquire. It’s additionally essential to observe portion sizes; overeating any meals kind may cause undesirable kilos.

Get transferring & be lively

Getting lively is any other nice technique to keep away from gaining weight on Zoloft. Workout is helping burn energy and spice up metabolism, which is very important for keeping up a wholesome weight. You don’t have to enroll in a pricey fitness center or purchase fancy apparatus; merely strolling across the block or doing mild stretching at house will incessantly do the trick.

Make sleep a concern

Making sleep a concern is very important for psychological fitness on the whole. Loss of sleep can result in larger urge for food because of hormones being out of stability, making it more difficult for individuals who take this antidepressant drugs to deal with their present weight and save you additional positive factors from happening one day. Stay a wholesome sleep regimen and goal for 7-8 hours consistent with night time. You’ll be able to additionally take quick naps all over the day.

Communicate on your physician about switching drugs

Communicate along with your physician about switching your antidepressant remedy if essential. 

“The easiest way to keep away from weight acquire because of Zoloft is to paintings carefully along with your psychiatrist. When you’re gaining weight, let your physician know so you’ll be able to be switched to any other antidepressant.”

Talkspace therapist Bisma Anwar, LMHC

In case your melancholy prognosis and remedy plan counsel drugs for melancholy, your physician could possibly counsel different SSRIs which can be much less more likely to purpose weight acquire.

Communicate to Your Physician About Zoloft Aspect Results

It’s essential for any person taking into consideration beginning an antidepressant like Zoloft to grasp the hazards related to its use. 

If you happen to’re fearful about Zoloft and weight acquire or different uncomfortable side effects, percentage your issues along with your physician.

On-line psychiatry from Talkspace may give skilled steerage as you navigate the prospective uncomfortable side effects of a prescribed drugs. If you happen to’re desirous about weight acquire on Zoloft, discover your remedy choices with a psychiatrist. Take keep watch over of your fitness as of late by way of in quest of the best psychiatrist-prescribed drugs for you.


  1. Arterburn D, Sofer T, Boudreau D, et al. Lengthy-term weight exchange after beginning second-generation antidepressants. Magazine of Scientific Drugs. 2016;5(4):48. doi:10.3390/jcm5040048. https://www.mdpi.com/2077-0383/5/4/48. Accessed December 16, 2022.
  2. Gafoor R, Sales space HP, Gulliford MC. Antidepressant usage and prevalence of weight acquire all the way through 10 years’ follow-up: Inhabitants founded cohort learn about. BMJ. 2018. doi:10.1136/bmj.k1951. https://www.bmj.com/content material/361/bmj.k1951. Accessed December 16, 2022.
  3. Ozsoy S, Besirli A, Abdulrezzak U, Basturk M. Serum ghrelin and leptin ranges in sufferers with melancholy and the results of remedy. Psychiatry Investigation. 2014;11(2):167. doi:10.4306/pi.2014.11.2.167. https://www.ncbi.nlm.nih.gov/percent/articles/PMC4023091/. Accessed December 16, 2022.

Talkspace articles are written by way of skilled psychological health-wellness participants; they’re grounded in medical analysis and evidence-based practices. Articles are widely reviewed by way of our crew of medical professionals (therapists and psychiatrists of more than a few specialties) to verify content material is correct and on par with present business requirements.

Our objective at Talkspace is to give you the most recent, precious, and purpose data on psychological health-related subjects to be able to lend a hand readers make knowledgeable selections.

Articles comprise depended on third-party resources which can be both without delay connected to within the textual content or indexed on the backside to take readers without delay to the supply.

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