Home Mental Health What is the Distinction? — Talkspace

What is the Distinction? — Talkspace

What is the Distinction? — Talkspace


Revealed on: 03 Apr 2023

Celexa vs Lexapro

Celexa and Lexapro are two commonplace psychiatrist prescribed drugs for psychological fitness problems. Each are FDA-approved to regard melancholy, even if Lexapro may also be used for adults with nervousness. They each belong to a category of substances known as selective serotonin reuptake inhibitors (SSRIs). Whilst Celexa or Lexapro have an identical results at the frame, there are some key variations between them:

  • Lexapro is authorised to regard nervousness — even though each are used off-label for different stipulations
  • Lexapro is also more practical than Celexa in treating signs of melancholy
  • Lexapro is a relatively more recent drug — it was once FDA-approved in 2002, while Celexa was once authorised in 1998
  • Lexapro is authorised to regard melancholy in adults and youngsters 12 years and older; Celexa is best used with adults

Proceed studying as we discover extra on this comparability of Celexa vs Lexapro. We’re shining a mild on how each and every of those drugs works, what they deal with, what Celexa and Lexapro negative effects you will have to pay attention to, and the way to make a choice which one is also best for you. 

“Either one of those drugs are categorized as SSRIs and prescribed for temper and nervousness problems. Celexa is FDA authorised and indicated for MDD and OCD. Lexapro is FDA authorised and indicated for MDD and GAD. Alternatively, psychiatrists would possibly prescribe those for different scientific stipulations or as an off label drugs.”

Talkspace psychiatrist Dr. Muhammad Munir, MD, DFAPA

How They Paintings

When taking a look at Lexapro vs Celexa, it’s a very powerful to know the way those medication paintings. They each belong to a category of substances known as selective serotonin reuptake inhibitors (SSRIs). SSRIs building up serotonin ranges within the mind, which is thought to assist control temper.

Similarities between Lexapro vs Celexa:

  • Each save you the reuptake of serotonin via expanding ranges, which improves depressive signs
  • Each have generic variations
  • Each have an identical negative effects
  • Each have withdrawal signs
  • Each have rather few considerations about drug interplay with different drugs 
  • Each are best to be had via prescription, however nor is categorized as “managed medication”

Variations between Celexa and Lexapro:

  • Dosage is other
  • Lexapro will also be administered in both liquid or pill shape, however Celexa remedy best comes as tablets
  • Uncomfortable side effects would possibly fluctuate 
  • Celexa is much more likely to motive QT prolongation — a center disturbance — at upper doses


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Stipulations They Deal with

Celexa and Lexapro are each FDA-approved to regard main depressive dysfunction (MDD), and Lexapro can deal with generalized nervousness dysfunction (GAD) in adults. They can be used off-label for different psychological fitness stipulations. 

Celexa antidepressant drugs can be utilized off-label to regard:

Lexapro antidepressant drugs can be utilized off-label to regard:

Does Lexapro paintings higher than Celexa for nervousness?

An important distinction between Celexa and Lexapro is efficacy. Some research counsel that sufferers with generalized nervousness dysfunction (GAD) reply higher to Lexapro than Celexa for his or her situation. 

Alternatively, it’s necessary to notice that each and every user responds otherwise to drugs. The whole thing from the efficacy to how lengthy it takes for Lexapro to paintings will also be other throughout people. It’s all the time absolute best to talk about your choices together with your physician or healthcare supplier so you’ll be able to make the most efficient selections about which drugs is best for you and your ​​nervousness and melancholy signs.

Aspect Results

Commonplace negative effects related to each medication come with: 

  • Nausea
  • Headache
  • Insomnia or drowsiness
  • Dry mouth 
  • Greater sweating
  • Diarrhea 

Some other people would possibly enjoy sexual negative effects, together with diminished libido or problem reaching orgasm whilst taking both drug. Different attainable negative effects come with weight achieve, particularly with regard to Lexapro weight achieve, or loss and adjustments in urge for food. 

Aspect Impact Lexapro Celexa
Dry mouth
Sleep problems
Tremors Very uncommon
Congestion/runny nostril
Sexual issues
Dizziness Very uncommon
Seizures With upper doses and in other people with seizure dysfunction
*Low sodium ranges
*Possibility of bleeding
*Unusual center rhythm
*Manic episodes in other people with bipolar dysfunction

*Denotes extra critical negative effects

“A number of negative effects are dose-dependent, at upper doses. Those come with behind schedule ejaculation, fatigue, sleepiness, insomnia, sweating, and yawning.”

Talkspace psychiatrist Dr. Muhammad Munir, MD, DFAPA

Does Celexa have much less negative effects than Lexapro?

Normally, most of the people in finding that the negative effects of both drug are gentle in comparison to the advantages they see. That stated, some other people do file experiencing fewer negative effects when taking one over the opposite. 

If you are feeling you’re having too many hostile reactions from any drugs, talk together with your physician so they are able to alter your dosage or transfer drugs.


Dosage is some other distinction between Celexa and Lexapro. Dosage can range relying on components reminiscent of age and scientific historical past of sufferers, however the most often really useful beginning doses are: 

  • Celexa: 20 mg consistent with day 
  • Lexapro: 10 mg consistent with day  

“The dose increment is finished at other durations and over other length. There’s a distinction within the signs reaction, the dosage prescribed is other Celexa 10/2/40 mg vs Lexapro 10/20 mg.”

Talkspace psychiatrist Dr. Muhammad Munir, MD, DFAPA

Decide if Celexa or Lexapro Is Proper for You with Talkspace

Deciding which drugs is true for you’ll be able to be tricky. Even if taking the similar form of antidepressant—like an SSRI reminiscent of Celexa or Lexapro — drugs can have an effect on other people otherwise. Regardless, most of the people in finding drugs is more practical when blended with treatment. That’s why Talkspace provides on-line psychiatry and treatment services and products, the place authorized psychological fitness execs let you decide the most efficient remedy plan for you and your particular scenario. 

With Talkspace, you obtain customized care adapted in particular against serving to you arrange your psychological fitness situation so you’ll be able to succeed in long-lasting effects. Don’t hesitate to succeed in out and get started your adventure against higher psychological fitness nowadays.  


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  2. Gorman JM, Korotzer A, Su G. Efficacy comparability of escitalopram and citalopram within the remedy of main depressive dysfunction: Pooled evaluation of placebo-controlled trials. CNS Spectrums. 2002;7(S1):40-44. doi:10.1017/s1092852900028595. https://pubmed.ncbi.nlm.nih.gov/15131492/. Accessed December 14, 2022.
  3. Escitalopram (Lexapro). NAMI. https://www.nami.org/About-Psychological-Sickness/Therapies/Psychological-Well being-Medicines/Varieties-of-Medicine/Escitalopram-%28Lexapropercent29#: Accessed December 14, 2022. 

Talkspace articles are written via skilled psychological health-wellness individuals; they’re grounded in medical analysis and evidence-based practices. Articles are broadly reviewed via our staff of scientific professionals (therapists and psychiatrists of quite a lot of specialties) to verify content material is correct and on par with present trade requirements.

Our function at Talkspace is to give you the most recent, precious, and function data on psychological health-related subjects with a purpose to assist readers make knowledgeable selections.

Articles include depended on third-party resources which might be both immediately connected to within the textual content or indexed on the backside to take readers immediately to the supply.

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